72-hour STI prevention plan — Clinician-reviewed | My London Pharmacy
Reddit-only: REDDIT11 for 11% off your first consultation — auto-applied at checkout.
UK-registered pharmacy
BASHH-informed · UK clinician-reviewed

STI prevention, taken within a 72-hour window.

A short clinical consultation, reviewed by UK-registered clinicians, leading to a personalised prevention plan you take within 72 hours of condomless sex. It significantly reduces the risk of bacterial STIs — particularly chlamydia and syphilis — and is part of current UK clinical guidance for people at higher risk.

£53.39 £59.99 for a 15-treatment prevention plan REDDIT11 applied
Takes ~5 minutes · UK clinician-reviewed · You only pay if approved.
Discreet prevention plan delivery
UK-registered pharmacy Clinician-prescribed Discreet same-day dispatch Excellent on Trustpilot
If any of this sounds familiar

You're not the first person to think about this after a Friday night.

Most people who come to us for a prevention consultation aren't reckless. They're informed, sexually active adults who know condoms aren't always used, and want a clinically-backed option for the windows when they aren't. Here's what we hear most.

The Sunday-morning panic

You're not sure if you were safe. The earliest you can get a useful STI test is two weeks away. The waiting is awful and the not-knowing is worse.

"A post-exposure prevention plan exists for exactly this window — taken within 72 hours."

GUM clinics that take three weeks to call back

NHS sexual health services are excellent but stretched. By the time you get an appointment, the 72-hour window is long gone.

"A private consultation gets you a clinical decision within the window when prevention is still possible."

Tired of antibiotic rounds after positive tests

If you've had chlamydia or syphilis once, the treatment isn't fun and the partner-tracing conversations are worse. Prevention is calmer than cure.

"Clinical evidence suggests significant reduction in these infections for people at higher exposure risk."

Already on PrEP, still worried about STIs

PrEP is brilliant for HIV. It doesn't do anything for chlamydia, syphilis, or gonorrhoea. A bacterial-STI prevention plan is the counterpart.

"Many of our patients pair this prevention plan with their existing PrEP — the two work alongside each other."

The basics

What the prevention plan involves.

It's a single, clinician-prescribed dose you take within 72 hours of condomless sex. The earlier the better — within 24 hours is ideal. The consultation checks your medical history, looks for anything that would make it unsafe for you, and confirms eligibility against current UK guidance.

When suitable, the plan significantly reduces the risk of bacterial STIs — particularly chlamydia and syphilis, with a smaller effect on gonorrhoea. It does not protect against HIV, herpes, HPV, hepatitis, or other viral infections.

  • Format Single oral dose, taken after exposure
  • When to take Within 72h of condomless sex (ideally <24h)
  • Works on Chlamydia · syphilis · partial gonorrhoea
  • Required UK clinician consultation and prescription
Clinician-reviewed prevention plan
How it works

Three steps. About five minutes.

No pressure, no countdown timers, no spots-filling-fast. You only pay if approved.

1

Free consultation

A short online assessment so a UK clinician can check it's safe and appropriate for you. About 5 minutes.

2

Clinician review

A UK-registered prescriber reviews your answers. Around 1 in 6 consultations aren't suitable — and you pay nothing if so.

3

Discreet delivery

Plain packaging, dispatched same day for next-working-day delivery across the UK.

What the evidence shows

The numbers, plainly.

Two large randomised clinical trials, plus follow-up real-world data, have produced the figures below. UK BASHH issued an interim position statement in 2024 supporting post-exposure prevention for men who have sex with men and trans women with recurrent bacterial STIs.

~70%
Reduction in chlamydia and syphilis among MSM and trans women in randomised trial data.
~50%
Reduction in gonorrhoea — smaller, because of higher tetracycline resistance.
<72h
Window after exposure during which the plan is effective. Sooner is better.

Sources: BASHH Interim Position Statement on bacterial STI post-exposure prophylaxis (2024); Luetkemeyer et al., NEJM 2023; Molina et al., Lancet ID 2023. Numbers vary by study population and STI type.

Who this prevention plan is for

It's not for everyone. Here's the honest split.

Every consultation is assessed against current UK clinical guidance. If it's not suitable, you'll be told why and refunded. That's the point of a real prescriber, not a vending machine.

Generally suitable

  • Men who have sex with men, trans women, and non-binary people in similar contexts
  • Already on PrEP and wanting bacterial-STI cover too
  • People with a history of recurrent chlamydia or syphilis
  • Sex workers and others with frequent condomless exposure
  • People in open or polyamorous relationships
  • Anyone over 18 with a recent condomless exposure who wants the option

Probably not suitable (we'll flag)

  • Tetracycline-class allergies
  • Pregnancy or trying to conceive
  • Severe liver impairment
  • Certain interacting medications — flagged at consultation
  • Under 18
  • Frequent / daily use — this is a targeted prevention plan, not daily prophylaxis
Honest comparison

How this stacks up against the alternatives.

No prevention method is perfect on its own — and we'll never tell you otherwise. Most patients pair a post-exposure prevention plan with PrEP, condoms when practical, and regular testing. Here's how the options compare.

Our prevention plan
NHS GUM clinic
No prevention
Wait time
Consultation today · delivery next working day
Often 2–3 weeks for an appointment
n/a
Cost
£53.39 for a 15-treatment plan with REDDIT11
Free where available — patchy by region
Cost of treatment if you contract one
Covers chlamydia / syphilis
Significant reduction (~70% in trials)
Treatment after-the-fact, not prevention
No protection
Covers HIV / HPV / herpes
No — pair with PrEP and condoms
Testing only
No protection
Privacy
Plain packaging · no GP record sharing by default
Confidential but in person
n/a
Antibiotic stewardship
Reviewed at consultation · targeted use only
Active clinician oversight
Higher likelihood of needing antibiotics for treatment
What it isn't

Being honest about the limits.

Selling something properly means saying what it doesn't do, too. This prevention plan works inside a specific window, against specific infections, when used responsibly. It's not a magic shield.

Not a replacement for condoms.

Condoms remain the only single-method protection against HIV, HPV, and herpes. This plan works alongside them, not instead.

Not a replacement for PrEP.

If HIV is a concern, you need PrEP. This plan only addresses bacterial STIs. The two combine well.

Not a replacement for testing.

Regular STI testing (every 3–6 months for sexually active people) matters whether or not you use this plan. We can advise on options.

Not for daily use.

This is taken after exposure, not as a daily preventive. Daily use raises antibiotic resistance concerns and isn't supported by current evidence.

Not 100% effective.

Trial data suggests roughly 70% reduction for chlamydia and syphilis, less for gonorrhoea. It significantly lowers risk; it doesn't eliminate it.

Not for everyone.

Pregnancy, certain allergies, and certain interacting medications rule it out. The consultation catches this — you'll be told and refunded.

Pricing

Transparent. No subscription. No minimum term.

£53.39 £59.99
15-treatment prevention plan · 11% off with REDDIT11

That works out to £3.56 per single-dose treatment. No subscription. Order more when you need it. Cancel any time.

  • 11% off auto-applied with REDDIT11
  • No subscription · no minimum term
  • Refunded if not clinically suitable
  • Same-day dispatch in plain packaging
  • UK-registered clinicians review every consultation
  • UK-registered pharmacy
Who's prescribing

Real UK clinicians, named and registered.

Senior Lead Prescriber

Our Senior Lead Prescriber and the wider clinical team review every consultation personally. No algorithms deciding eligibility — a real clinician checks your history, looks for interactions, and signs off (or doesn't) on every prescription. Every prescriber is UK-registered, and you can verify their registration on the GPhC public register.

What people say

Real reviews, real stories.

★★★★★

"Super helpful. Item arrived quickly and well tracked. Very happy with the support received to date."

Jane C · Oct 2024
★★★★★

"Great company. Very responsive to any messages or emails. Will always sort any problems out immediately. Wouldn't go anywhere else."

J Fox · Sept 2024
★★★★★

"I've used My London Pharmacy for a number of months — efficient, delivery always on time, excellent customer service, queries answered in super quick time."

Gianetta · Sept 2024
★★★★★

"They've been amazing. I'm very thorough and their examination was thorough too. Medication dispatched promptly, communication on point. 100% recommend."

Mary Holmes · Sept 2024

Read all reviews on Trustpilot →

Questions you might be sitting with

FAQs.

Is this prevention plan legal in the UK?

Yes. The treatment used is a long-established, UK-licensed antibiotic class with decades of safety data. Its application for post-exposure STI prevention is off-label — meaning the original product licence covers treatment of bacterial infections rather than prevention — but off-label prescribing is normal clinical practice when supported by evidence. UK BASHH issued an interim position statement in 2024 supporting post-exposure prevention for higher-risk MSM and trans women.

How effective is it really?

Randomised trials in MSM and trans women showed roughly 70% reduction in chlamydia and syphilis, and around 50% reduction in gonorrhoea (lower because of higher tetracycline resistance). Effectiveness depends on starting the plan within 72 hours of exposure — sooner is better. It's not a guarantee; it's a significant reduction in risk.

Can I use this with PrEP?

Yes — this prevention plan and PrEP are commonly used together. PrEP covers HIV, this plan covers most bacterial STIs. There are no significant interactions between them. Many patients using this consultation are also on PrEP.

What about antibiotic resistance?

It's a legitimate concern and we don't dismiss it. The plan is targeted (used after exposure, not daily), reviewed by a clinician for appropriateness, and most useful for people who would otherwise need repeated treatments for actual infections. The current clinical consensus is that the individual resistance risk is outweighed by the prevention benefit when used in eligible groups — but it's actively discussed in every consultation.

What are the side effects?

The most common are mild nausea and increased sun sensitivity. Taking the dose with food and water reduces nausea. Use sunscreen if you're spending time outdoors. Less common: indigestion, oesophageal irritation if taken without enough water. Severe reactions are rare and listed in the patient information leaflet that comes with your prescription.

Can I use it every time I have sex?

The evidence supports use after condomless exposure — not daily, and not "prophylactically before" sex. Frequent use needs a clinical conversation: if you'd use it more than ~3 times a week, we'll usually want to talk through whether a different approach (or more frequent testing) makes sense.

How discreet is delivery?

Plain outer packaging, no pharmacy branding or product information visible on the outside. Standard Royal Mail Tracked 24. If you'd prefer to collect from a pickup point, that can be arranged at checkout.

What if I'm declined?

About 1 in 6 consultations aren't suitable — usually due to allergies, interacting medications, or specific medical history. If declined, you've paid nothing, and a clinician will tell you why. If there's an obvious alternative we'll point to it.

How do I cancel or stop?

There's nothing to cancel — you buy what you need, when you need it. No subscription, no minimum term, no recurring charges. Order a 15-treatment plan now, use them over six months, order more whenever.

Will my GP know?

Only if you ask us to share with them. Private prescriptions stay between you and our pharmacy unless you opt in to update your NHS record. We can integrate with the NHS Summary Care Record if you'd prefer — your choice.

Still have a question? Email our clinical team — same-day response on weekdays.

If you're ready

The consultation takes about five minutes.

No countdown timer, no fake scarcity, no influencer code. Just a UK clinician-reviewed consultation. You only pay if approved.

Start free consultation →

REDDIT11 applies automatically · 11% off your first consultation

Available payment methods