Better Sleep for Insomnia—Supporting Rest and Overall Wellbeing

QUVIVIQ (daridorexant) is a prescription-only medicine used to treat insomnia in adults who struggle to fall asleep, stay asleep, or experience poor sleep quality that affects daytime functioning.

Unlike traditional sleeping tablets that rely on sedation, QUVIVIQ targets a brain system called orexin, which helps regulate the body’s natural sleep-wake rhythm. By blocking the orexin receptors (OX1R and OX2R), it promotes better sleep at night without making you feel groggy the next day.

Some individuals may notice improvements in their sleep within a few days, while others may require more time. The onset of action can vary depending on the severity of your insomnia and other health factors.

The standard adult dose is 50 mg taken once before bedtime. In some cases, your doctor may prescribe a lower dose, such as 25 mg. The maximum daily dose is 50 mg, and you should never take more than prescribed.

If you forget to take your tablet at bedtime, skip the dose and wait until the next evening. Do not take QUVIVIQ during the night or double up the next day.

Yes, common side effects include tiredness, headache, and daytime drowsiness. In rare cases, some people may experience unusual sleep behaviours (such as sleepwalking), hallucinations, sleep paralysis, or worsening of depression. Always contact your GP or pharmacist if you notice anything concerning.

Yes. Do not take QUVIVIQ if you have narcolepsy or if you are allergic to any of its ingredients. It should be used with caution if you have a history of mental health issues, breathing disorders like sleep apnoea, liver problems, or are pregnant or breastfeeding.

QUVIVIQ is a controlled medicine due to its potential for dependence or misuse.

No. Alcohol can heighten the sedative effects of QUVIVIQ, which may be dangerous. It’s best to avoid alcohol completely while using this medication.

While no dose adjustment is typically needed for adults over 65, caution is recommended, especially in those over 75, as data is limited. Speak with your healthcare provider for personalised advice.

Inform your prescriber of all medications and supplements you’re taking. QUVIVIQ may interact with certain drugs, especially those that affect the central nervous system or are metabolised by CYP3A4 enzymes. Avoid combining with other sedating medications unless directed.

You should not take QUVIVIQ if you have:

• Narcolepsy

• Known allergy to daridorexant or any excipients

• Severe liver impairment

• Are using strong CYP3A4 inhibitors

Always consult your GP before starting a new medicine.

You can safely order QUVIVIQ at My London Pharmacy, we provide free consultations and expert support. Get discreet delivery of your prescription directly to your door — safely and conveniently.